6I2Q

Crystal structure of the wild-type SucA domain of Mycobacterium smegmatis KGD (alpha-ketoglutarate decarboxylase), in complex with GarA

Replaces:  2XT9

Summary for 6I2Q

• Entry DOI: 10.2210/pdb6i2q/pdb
• Descriptor: Multifunctional 2-oxoglutarate metabolism enzyme, Glycogen accumulation regulator GarA, THIAMINE DIPHOSPHATE, ... (6 entities in total)
• Functional Keywords: oxoglutarate dehydrogenase, decarboxylase, oxidoreductase
• Biological source: Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155); More
• Total number of polymer chains: 2
• Total formula weight: 109768.64

Authors

Wagner, T.,Bellinzoni, M.,Alzari, P.M. (deposition date: 2018-11-01, release date: 2019-05-22, Last modification date: 2024-01-24)

• Primary citation: Wagner, T.,Andre-Leroux, G.,Hindie, V.,Barilone, N.,Lisa, M.N.,Hoos, S.,Raynal, B.,Vulliez-Le Normand, B.,O'Hare, H.M.,Bellinzoni, M.,Alzari, P.M.; Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.; Sci.Signal., 12:-, 2019; PubMed: 31064884; DOI: 10.1126/scisignal.aav9504

Experimental method

X-RAY DIFFRACTION (2.15 Å)