6I2P

Crystal structure of the Mycobacterium tuberculosis PknB kinase domain (L33E mutant) in complex with its substrate GarA

6I2P の概要

• エントリーDOI: 10.2210/pdb6i2p/pdb
• 分子名称: Serine/threonine-protein kinase PknB, Glycogen accumulation regulator GarA, UNK-UNK-UNK-UNK-UNK, ... (7 entities in total)
• 機能のキーワード: kinase, fha-domain protein, signaling protein
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 97476.74

構造登録者

Andre-Leroux, G.,Hindie, V.,Barilone, N.,Bellinzoni, M.,Alzari, P.M. (登録日: 2018-11-01, 公開日: 2019-05-22, 最終更新日: 2024-01-24)

• 主引用文献: Wagner, T.,Andre-Leroux, G.,Hindie, V.,Barilone, N.,Lisa, M.N.,Hoos, S.,Raynal, B.,Vulliez-Le Normand, B.,O'Hare, H.M.,Bellinzoni, M.,Alzari, P.M.; Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling.; Sci.Signal., 12:-, 2019; PubMed: 31064884; DOI: 10.1126/scisignal.aav9504

実験手法

X-RAY DIFFRACTION (2.37 Å)