6I1D

Structure of the Ysh1-Mpe1 nuclease complex from S.cerevisiae

6I1D の概要

• エントリーDOI: 10.2210/pdb6i1d/pdb
• 分子名称: Endoribonuclease YSH1, Protein MPE1, ZINC ION, ... (5 entities in total)
• 機能のキーワード: pre-mrna, mrna, nuclease, endonuclease, cleavage, polyadenylation, polya, cpf, metallo-beta-lactamase, 3' ends, gene regulation
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 71756.75

構造登録者

Hill, C.H.,Boreikaite, V.,Kumar, A.,Casanal, A.,Kubik, P.,Degliesposti, G.,Maslen, S.,Mariani, A.,von Loeffelholz, O.,Girbig, M.,Skehel, M.,Passmore, L.A. (登録日: 2018-10-28, 公開日: 2019-02-13, 最終更新日: 2024-01-24)

• 主引用文献: Hill, C.H.,Boreikaite, V.,Kumar, A.,Casanal, A.,Kubik, P.,Degliesposti, G.,Maslen, S.,Mariani, A.,von Loeffelholz, O.,Girbig, M.,Skehel, M.,Passmore, L.A.; Activation of the Endonuclease that Defines mRNA 3' Ends Requires Incorporation into an 8-Subunit Core Cleavage and Polyadenylation Factor Complex.; Mol.Cell, 73:1217-1231.e11, 2019; PubMed: 30737185; DOI: 10.1016/j.molcel.2018.12.023

実験手法

X-RAY DIFFRACTION (2.28 Å)