6I0Q

Crystal structure of BTB domain of KCTD16 hexamer

6I0Q の概要

• エントリーDOI: 10.2210/pdb6i0q/pdb
• 分子名称: BTB/POZ domain-containing protein KCTD16 (2 entities in total)
• 機能のキーワード: kctd, gaba(b) receptor, receptor associated protein, structural protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12176.01

構造登録者

Kasaragod, V.B.,Sereikaite, V.,Stromgaard, K.,Schindelin, H. (登録日: 2018-10-26, 公開日: 2019-10-02, 最終更新日: 2024-01-24)

• 主引用文献: Sereikaite, V.,Fritzius, T.,Kasaragod, V.B.,Bader, N.,Maric, H.M.,Schindelin, H.,Bettler, B.,Stromgaard, K.; Targeting the gamma-Aminobutyric Acid Type B (GABAB) Receptor Complex: Development of Inhibitors Targeting the K+Channel Tetramerization Domain (KCTD) Containing Proteins/GABABReceptor Protein-Protein Interaction.; J.Med.Chem., 62:8819-8830, 2019; PubMed: 31509708; DOI: 10.1021/acs.jmedchem.9b01087

実験手法

X-RAY DIFFRACTION (2.3 Å)