6I0K
Structure of quinolinate synthase in complex with 4-mercaptophthalic acid
Summary for 6I0K
Entry DOI | 10.2210/pdb6i0k/pdb |
Descriptor | Quinolinate synthase A, IRON/SULFUR CLUSTER, 4-mercaptoidenecyclohexa-2,5-diene-1,2-dicarboxylic acid, ... (6 entities in total) |
Functional Keywords | nad biosynthesis, iron sulfur cluster, transferase |
Biological source | Thermotoga maritima MSB8 |
Total number of polymer chains | 1 |
Total formula weight | 35320.86 |
Authors | Volbeda, A.,Fontecilla-Camps, J.C. (deposition date: 2018-10-26, release date: 2019-03-20, Last modification date: 2024-01-24) |
Primary citation | Saez Cabodevilla, J.,Volbeda, A.,Hamelin, O.,Latour, J.M.,Gigarel, O.,Clemancey, M.,Darnault, C.,Reichmann, D.,Amara, P.,Fontecilla-Camps, J.C.,Ollagnier de Choudens, S. Design of specific inhibitors of quinolinate synthase based on [4Fe-4S] cluster coordination. Chem.Commun.(Camb.), 55:3725-3728, 2019 Cited by PubMed: 30855610DOI: 10.1039/c8cc09023h PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.64 Å) |
Structure validation
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