6HY7

Crystal structure of alpha9 nAChR extracellular domain in complex with alpha-conotoxin RgIA

Summary for 6HY7

Entry DOI	10.2210/pdb6hy7/pdb
Descriptor	Neuronal acetylcholine receptor subunit alpha-9, Alpha-conotoxin RgIA, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	alpha9, ion channel, nachr, acetylcholine, conotoxin, rgia, antagonist, toxin
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	27389.40
Authors	Giastas, P.,Zouridakis, M. (deposition date: 2018-10-19, release date: 2019-05-22, Last modification date: 2024-01-24)
Primary citation	Zouridakis, M.,Papakyriakou, A.,Ivanov, I.A.,Kasheverov, I.E.,Tsetlin, V.,Tzartos, S.,Giastas, P. Crystal Structure of the Monomeric Extracellular Domain of alpha 9 Nicotinic Receptor Subunit in Complex With alpha-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to alpha 9 alpha 10 Nicotinic Receptors. Front Pharmacol, 10:474-474, 2019 Cited by PubMed: 31118896 DOI: 10.3389/fphar.2019.00474 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.26 Å)

Structure validation