6HY7

Crystal structure of alpha9 nAChR extracellular domain in complex with alpha-conotoxin RgIA

6HY7 の概要

分子名称Neuronal acetylcholine receptor subunit alpha-9, Alpha-conotoxin RgIA, N-ACETYL-D-GLUCOSAMINE, ... (5 entities in total)
機能のキーワードalpha9, ion channel, nachr, acetylcholine, conotoxin, rgia, antagonist, toxin
由来する生物種Homo sapiens (Human)
詳細
ポリマー鎖数2
分子量合計27389.4
構造登録者
Giastas, P.,Zouridakis, M. (登録日: 2018-10-19, 公開日: 2019-05-22, 最終更新日: 2019-06-05)
主引用文献
Zouridakis, M.,Papakyriakou, A.,Ivanov, I.A.,Kasheverov, I.E.,Tsetlin, V.,Tzartos, S.,Giastas, P.
Crystal Structure of the Monomeric Extracellular Domain of alpha 9 Nicotinic Receptor Subunit in Complex With alpha-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to alpha 9 alpha 10 Nicotinic Receptors.
Front Pharmacol, 10:474-474, 2019
PubMed: 31118896 (主引用文献が同じPDBエントリー)
DOI: 10.3389/fphar.2019.00474
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (2.26 Å)
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.24714 0.9% 1.5% 2.7%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
検証レポート(詳細版)をダウンロード

他の静止画像(非対称単位)

Molmil generated image of 6hy7
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Molmil generated image of 6hy7
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Molmil generated image of 6hy7
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