6HY7

Crystal structure of alpha9 nAChR extracellular domain in complex with alpha-conotoxin RgIA

6HY7 の概要

• エントリーDOI: 10.2210/pdb6hy7/pdb
• 分子名称: Neuronal acetylcholine receptor subunit alpha-9, Alpha-conotoxin RgIA, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: alpha9, ion channel, nachr, acetylcholine, conotoxin, rgia, antagonist, toxin
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27389.40

構造登録者

Giastas, P.,Zouridakis, M. (登録日: 2018-10-19, 公開日: 2019-05-22, 最終更新日: 2024-01-24)

• 主引用文献: Zouridakis, M.,Papakyriakou, A.,Ivanov, I.A.,Kasheverov, I.E.,Tsetlin, V.,Tzartos, S.,Giastas, P.; Crystal Structure of the Monomeric Extracellular Domain of alpha 9 Nicotinic Receptor Subunit in Complex With alpha-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to alpha 9 alpha 10 Nicotinic Receptors.; Front Pharmacol, 10:474-474, 2019; PubMed: 31118896; DOI: 10.3389/fphar.2019.00474

実験手法

X-RAY DIFFRACTION (2.26 Å)