6HVL

CdaA complex with c-di-AMP and AMP

Summary for 6HVL

Entry DOI	10.2210/pdb6hvl/pdb
Descriptor	Diadenylate cyclase, (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, COBALT (II) ION, ... (6 entities in total)
Functional Keywords	di-adenylate cyclase, second messenger, complex, c-di-amp, amp, transferase
Biological source	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
Total number of polymer chains	2
Total formula weight	39897.74
Authors	Heidemann, J.L.,Neumann, P.,Ficner, R. (deposition date: 2018-10-11, release date: 2019-06-05, Last modification date: 2024-01-24)
Primary citation	Heidemann, J.L.,Neumann, P.,Dickmanns, A.,Ficner, R. Crystal structures of the c-di-AMP-synthesizing enzyme CdaA. J.Biol.Chem., 294:10463-10470, 2019 Cited by PubMed: 31118276 DOI: 10.1074/jbc.RA119.009246 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation