6HUZ

HmdII from Desulfurobacterium thermolithotrophum reconstituted with Fe-guanylylpyridinol (FeGP) cofactor and co-crystallized with methenyl-tetrahydrofolate form B

6HUZ の概要

• エントリーDOI: 10.2210/pdb6huz/pdb
• 分子名称: Coenzyme F420-dependent N(5),N(10)-methenyltetrahydromethanopterin reductase-related protein, iron-guanylyl pyridinol cofactor, 5,10-Methenyltetrahydrofolate, ... (7 entities in total)
• 機能のキーワード: hydrogenase, h2-activation, lateral gene-transfer, cofactor biosynthesis, tetrahydromethanopterin, tetrahydrofolate, paralog, sulfur-reducing bacteria, metalloenzyme, oxidoreductase
• 由来する生物種: Desulfurobacterium thermolithotrophum DSM 11699
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42451.98

構造登録者

Watanabe, T.,Wagner, T.,Huang, G.,Kahnt, J.,Ataka, K.,Ermler, U.,Shima, S. (登録日: 2018-10-09, 公開日: 2019-01-09, 最終更新日: 2024-01-24)

• 主引用文献: Watanabe, T.,Wagner, T.,Huang, G.,Kahnt, J.,Ataka, K.,Ermler, U.,Shima, S.; The Bacterial [Fe]-Hydrogenase Paralog HmdII Uses Tetrahydrofolate Derivatives as Substrates.; Angew. Chem. Int. Ed. Engl., 58:3506-3510, 2019; PubMed: 30600878; DOI: 10.1002/anie.201813465

実験手法

X-RAY DIFFRACTION (1.85 Å)