6HSV

Engineered higher-order assembly of Cholera Toxin B subunits via the addition of C-terminal parallel coiled-coiled domains

6HSV の概要

• エントリーDOI: 10.2210/pdb6hsv/pdb
• 分子名称: Toxin B subunit, PHOSPHATE ION, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
• 機能のキーワード: cholera toxin b, ctb, parallel coiled coils, higher order assembly, self assembly, designed protein, nanotube, toxin
• 由来する生物種: Vibrio cholerae
• タンパク質・核酸の鎖数: 20
• 化学式量合計: 281394.02

構造登録者

Pearson, A.R.,Turnbull, W.B.,Ross, J.F.,Trinh, C.H.,Webb, M.E. (登録日: 2018-10-01, 公開日: 2019-03-20, 最終更新日: 2024-01-24)

• 主引用文献: Ross, J.F.,Wildsmith, G.C.,Johnson, M.,Hurdiss, D.L.,Hollingsworth, K.,Thompson, R.F.,Mosayebi, M.,Trinh, C.H.,Paci, E.,Pearson, A.R.,Webb, M.E.,Turnbull, W.B.; Directed Assembly of Homopentameric Cholera Toxin B-Subunit Proteins into Higher-Order Structures Using Coiled-Coil Appendages.; J.Am.Chem.Soc., 141:5211-5219, 2019; PubMed: 30856321; DOI: 10.1021/jacs.8b11480

実験手法

X-RAY DIFFRACTION (2.45 Å)