6HPS
Near-infrared dual bioluminescence imaging in vivo using infra-luciferin
Summary for 6HPS
Entry DOI | 10.2210/pdb6hps/pdb |
Descriptor | Luciferin 4-monooxygenase, [(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methyl ~{N}-[[2-[(~{E})-2-(6-oxidanyl-1,3-benzothiazol-2-yl)ethenyl]-1,3-thiazol-4-yl]carbonyl]sulfamate (2 entities in total) |
Functional Keywords | near-infrared bioluminescence imaging, p. pyralis luciferase, anl superfamily, ligase, adenylating enzymes, luciferase, domain alternation, fluorescent protein |
Biological source | Photinus pyralis (Common eastern firefly) |
Total number of polymer chains | 2 |
Total formula weight | 121235.23 |
Authors | Parkinson, G.N.,Stowe, C.,Anderson, J.C. (deposition date: 2018-09-21, release date: 2019-10-23, Last modification date: 2024-01-24) |
Primary citation | Stowe, C.L.,Burley, T.A.,Allan, H.,Vinci, M.,Kramer-Marek, G.,Ciobota, D.M.,Parkinson, G.N.,Southworth, T.L.,Agliardi, G.,Hotblack, A.,Lythgoe, M.F.,Branchini, B.R.,Kalber, T.L.,Anderson, J.C.,Pule, M.A. Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin. Elife, 8:-, 2019 Cited by PubMed: 31610848DOI: 10.7554/eLife.45801 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
Download full validation report