6HPO
Crystallographic structure of the catalytic domain of Human Phenylalanine Hydroxylase (hPAH CD) in complex with iron at 1.6 Angstrom
Summary for 6HPO
Entry DOI | 10.2210/pdb6hpo/pdb |
Descriptor | Phenylalanine-4-hydroxylase, FE (III) ION (3 entities in total) |
Functional Keywords | tetrahydrobiopterin, amino acid hydroxylases, phenylketonuria, allosteric regulation, metal binding protein, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 51984.75 |
Authors | Alcorlo Pages, M.,Innselset Flydal, M. (deposition date: 2018-09-21, release date: 2019-06-05, Last modification date: 2024-01-24) |
Primary citation | Flydal, M.I.,Alcorlo-Pages, M.,Johannessen, F.G.,Martinez-Caballero, S.,Skjærven, L.,Fernandez-Leiro, R.,Martinez, A.,Hermoso, J.A. Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. Proc.Natl.Acad.Sci.USA, 116:11229-11234, 2019 Cited by PubMed: 31118288DOI: 10.1073/pnas.1902639116 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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