6HOP
Human protein kinase CK2 alpha in complex with curcumin degradation products
Summary for 6HOP
Entry DOI | 10.2210/pdb6hop/pdb |
Descriptor | Casein kinase II subunit alpha, SULFATE ION, 1,2-ETHANEDIOL, ... (8 entities in total) |
Functional Keywords | kinase domain, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41220.80 |
Authors | Battistutta, R.,Lolli, G. (deposition date: 2018-09-18, release date: 2019-10-02, Last modification date: 2024-01-24) |
Primary citation | Cozza, G.,Zonta, F.,Dalle Vedove, A.,Venerando, A.,Dall'Acqua, S.,Battistutta, R.,Ruzzene, M.,Lolli, G. Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin. Febs J., 287:1850-1864, 2020 Cited by PubMed: 31661600DOI: 10.1111/febs.15111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.55 Å) |
Structure validation
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