6HOD
TRANSCRIPTIONAL REPRESSOR ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH BDM44848
Summary for 6HOD
Entry DOI | 10.2210/pdb6hod/pdb |
Descriptor | HTH-type transcriptional regulator EthR, 4-[3-(phenylsulfonylamino)prop-1-ynyl]benzenesulfonamide (3 entities in total) |
Functional Keywords | helix-turn-helix, dna binding protein, tetr-family, complex, inhibitor, drug design, tuberculosis, ethionamide |
Biological source | Mycobacterium tuberculosis CDC1551 |
Total number of polymer chains | 1 |
Total formula weight | 25278.39 |
Authors | Wintjens, R.,Wohlkonig, A. (deposition date: 2018-09-17, release date: 2018-12-26, Last modification date: 2024-01-24) |
Primary citation | Tanina, A.,Wohlkonig, A.,Soror, S.H.,Flipo, M.,Villemagne, B.,Prevet, H.,Deprez, B.,Moune, M.,Peree, H.,Meyer, F.,Baulard, A.R.,Willand, N.,Wintjens, R. A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR. Biochim Biophys Acta Proteins Proteom, 1867:248-258, 2018 Cited by PubMed: 30553830DOI: 10.1016/j.bbapap.2018.12.003 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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