6HO9

TRANSCRIPTIONAL REPRESSOR ETHR FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH BDM44825

6HO9 の概要

• エントリーDOI: 10.2210/pdb6ho9/pdb
• 分子名称: HTH-type transcriptional regulator EthR, 4-[4-(2-methylpropyl)-1,2,3-triazol-1-yl]-~{N}-[3,3,3-tris(fluoranyl)propyl]benzamide (3 entities in total)
• 機能のキーワード: helix-turn-helix, dna binding protein, tetr-family, complex, inhibitor, drug design, tuberculosis, ethionamide
• 由来する生物種: Mycobacterium tuberculosis CDC1551
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25268.32

構造登録者

Wintjens, R.,Wohlkonig, A. (登録日: 2018-09-17, 公開日: 2018-12-26, 最終更新日: 2024-01-24)

• 主引用文献: Tanina, A.,Wohlkonig, A.,Soror, S.H.,Flipo, M.,Villemagne, B.,Prevet, H.,Deprez, B.,Moune, M.,Peree, H.,Meyer, F.,Baulard, A.R.,Willand, N.,Wintjens, R.; A comprehensive analysis of the protein-ligand interactions in crystal structures of Mycobacterium tuberculosis EthR.; Biochim Biophys Acta Proteins Proteom, 1867:248-258, 2018; PubMed: 30553830; DOI: 10.1016/j.bbapap.2018.12.003

実験手法

X-RAY DIFFRACTION (1.8 Å)