6HN3
wildtype form (apo) of human GPX4 with Se-Cys46
Summary for 6HN3
Entry DOI | 10.2210/pdb6hn3/pdb |
Related | 6HKQ |
Descriptor | Phospholipid hydroperoxide glutathione peroxidase, CHLORIDE ION, ETHANOL, ... (5 entities in total) |
Functional Keywords | anti-oxidatve defense system, oxidoreductase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 20637.43 |
Authors | Hillig, R.C.,Moosmayer, D.,Hilpmann, A.,Hoffmann, J.,Schnirch, L.,Eaton, J.K.,Badock, V.,Gradl, S. (deposition date: 2018-09-13, release date: 2020-04-01, Last modification date: 2024-01-24) |
Primary citation | Moosmayer, D.,Hilpmann, A.,Hoffmann, J.,Schnirch, L.,Zimmermann, K.,Badock, V.,Furst, L.,Eaton, J.K.,Viswanathan, V.S.,Schreiber, S.L.,Gradl, S.,Hillig, R.C. Crystal structures of the selenoprotein glutathione peroxidase 4 in its apo form and in complex with the covalently bound inhibitor ML162. Acta Crystallogr D Struct Biol, 77:237-248, 2021 Cited by PubMed: 33559612DOI: 10.1107/S2059798320016125 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.01 Å) |
Structure validation
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