6HME

LOW-SALT STRUCTURE OF PROTEIN KINASE CK2 CATALYTIC SUBUNIT (ISOFORM CK2ALPHA; CSNK2A1 gene product) IN COMPLEX WITH THE INDENOINDOLE-TYPE INHIBITOR THN27

Summary for 6HME

• Entry DOI: 10.2210/pdb6hme/pdb
• Descriptor: Casein kinase II subunit alpha, 1,2-ETHANEDIOL, CHLORIDE ION, ... (7 entities in total)
• Functional Keywords: protein kinase ck2, casein kinase 2, catalytic subunit ck2alpha, csnk2a1, indenoindole-type inhibitor, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 85433.13

Authors

Niefind, K.,Lindenblatt, D.,Jose, J.,Le Borgne, M. (deposition date: 2018-09-12, release date: 2019-03-27, Last modification date: 2024-01-24)

• Primary citation: Lindenblatt, D.,Nickelsen, A.,Applegate, V.M.,Hochscherf, J.,Witulski, B.,Bouaziz, Z.,Marminon, C.,Bretner, M.,Le Borgne, M.,Jose, J.,Niefind, K.; Diacritic Binding of an Indenoindole Inhibitor by CK2 alpha Paralogs Explored by a Reliable Path to Atomic Resolution CK2 alpha ' Structures.; Acs Omega, 4:5471-5478, 2019; PubMed: 31559376; DOI: 10.1021/acsomega.8b03415

Experimental method

X-RAY DIFFRACTION (1.85 Å)