6HLR

Yeast RNA polymerase I elongation complex bound to nucleotide analog GMPCPP (core focused)

6HLR の概要

• エントリーDOI: 10.2210/pdb6hlr/pdb
• EMDBエントリー: 0238 0239 0240
• 分子名称: DNA-directed RNA polymerase I subunit RPA190, DNA-directed RNA polymerases I, II, and III subunit RPABC5, DNA-directed RNA polymerases I and III subunit RPAC2, ... (18 entities in total)
• 機能のキーワード: transcription, polymerase, nucleotide, elongation
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 15
• 化学式量合計: 547362.27

構造登録者

Tafur, L.,Sadian, Y.,Weis, F.,Muller, C.W. (登録日: 2018-09-11, 公開日: 2019-04-03, 最終更新日: 2024-05-15)

• 主引用文献: Tafur, L.,Sadian, Y.,Hanske, J.,Wetzel, R.,Weis, F.,Muller, C.W.; The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2.; Elife, 8:-, 2019; PubMed: 30913026; DOI: 10.7554/eLife.43204

実験手法

ELECTRON MICROSCOPY (3.18 Å)