6HL6

Factor Inhibiting HIF (FIH) in complex with zinc, NOG and iASPP(670-693)

Summary for 6HL6

• Entry DOI: 10.2210/pdb6hl6/pdb
• Descriptor: Hypoxia-inducible factor 1-alpha inhibitor, RelA-associated inhibitor, GLYCEROL, ... (7 entities in total)
• Functional Keywords: non-heme, dioxygenase, oxygenase, metal-binding, transcription, double stranded beta-helix, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, epigenetic regulation, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase, ankyrin repeat domain, apoptosis, p53 binding protein, ank repeat, sh3 domain, ankyrin repeats, gene regulation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 43797.08

Authors

Leissing, T.M.,Chowdhury, R.,Clifton, I.J.,Lu, X.,Schofield, C.J. (deposition date: 2018-09-10, release date: 2019-10-09, Last modification date: 2024-01-24)

• Primary citation: Leissing, T.M.,Chowdhury, R.,Clifton, I.J.,Lu, X.,Schofield, C.J.; Factor Inhibiting HIF (FIH) in complex with zinc, NOG and iASPP(670-693); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)