The ATAD2 bromodomain in complex with compound 17

Summary for 6HIE

DescriptorATPase family AAA domain-containing protein 2, (2~{R})-1-[2-[4,4-bis(fluoranyl)cyclohexyl]ethyl]-~{N}-(4-ethanoyl-1,3-thiazol-2-yl)piperazine-2-carboxamide, SULFATE ION, ... (4 entities in total)
Functional Keywordsbromodomain, atad2, inhibitor, complex, cytosolic protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight15950.06
Sledz, P.,Caflisch, A. (deposition date: 2018-08-29, release date: 2019-02-20)
Primary citation
Dolbois, A.
Hitting a moving target: simulations and crystallography study of ATAD2 bromodomain blockers
To Be Published,
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.23840 1.7%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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