6HI1

PI3 Kinase Delta in complex with 3[6(morpholin4yl)pyridin2yl]phenol

6HI1 の概要

• エントリーDOI: 10.2210/pdb6hi1/pdb
• 分子名称: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform, 3-(6-morpholin-4-ylpyridin-2-yl)phenol (3 entities in total)
• 機能のキーワード: kinase, drug discovery, complex, transferase
• 由来する生物種: Mus musculus (Mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 108079.96

構造登録者

Convery, M.A.,Summers, D.,Peace, S. (登録日: 2018-08-29, 公開日: 2019-09-11, 最終更新日: 2024-05-15)

• 主引用文献: Convery, M.A.,Summers, D.,Hobbs, H.,Jamieson, C.,Kennedy, A.R.,Pal, S.,Peace, S.,Pogany, P.,Upton, R.; A theoretical and experimental investigation into the conformational bias of aryl cyclopropylpyrans, novel bioisosteres for N-aryl morpholines.; To be published,

実験手法

X-RAY DIFFRACTION (2.07 Å)