6HHR

Hsp90 in complex with 5-(2,4-Dihydroxy-phenyl)-4-(2-fluoro-phenyl)-2,4-dihydro-[1,2,4]triazole-3-thione

Summary for 6HHR

Entry DOI	10.2210/pdb6hhr/pdb
Descriptor	Heat shock protein HSP 90-alpha, 3-[2,4-bis(oxidanyl)phenyl]-4-(2-fluorophenyl)-1~{H}-1,2,4-triazole-5-thione, SULFATE ION, ... (4 entities in total)
Functional Keywords	chaperone, atp binding
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	23662.78
Authors	Musil, D.,Lehman, M.,Eggenweiler, H.-M. (deposition date: 2018-08-29, release date: 2019-07-10)
Primary citation	Schuetz, D.A.,Bernetti, M.,Bertazzo, M.,Musil, D.,Eggenweiler, H.M.,Recanatini, M.,Masetti, M.,Ecker, G.F.,Cavalli, A. Predicting Residence Time and Drug Unbinding Pathway through Scaled Molecular Dynamics. J.Chem.Inf.Model., 59:535-549, 2019 Cited by PubMed: 30500211 DOI: 10.1021/acs.jcim.8b00614 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation