6HH9

Crystal structure of a two-domain esterase (CEX) active on acetylated mannans co-crystallized with mannopentaose

6HH9 の概要

• エントリーDOI: 10.2210/pdb6hh9/pdb
• 関連するPDBエントリー: 6HFZ
• 分子名称: GDSL-like protein, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-beta-D-mannopyranose, ... (4 entities in total)
• 機能のキーワード: esterase, carbohydrate, galactoglucomannan, deacetylation, biomass, gut flora, sugar binding protein
• 由来する生物種: Roseburia intestinalis L1-82
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 171784.97

構造登録者

Michalak, L.,La Rosa, S.L.,Rohr, A.K.,Aachmann, F.L.,Westereng, B. (登録日: 2018-08-27, 公開日: 2019-09-11, 最終更新日: 2024-01-17)

• 主引用文献: Michalak, L.,La Rosa, S.L.,Leivers, S.,Lindstad, L.J.,Rohr, A.K.,Lillelund Aachmann, F.,Westereng, B.; A pair of esterases from a commensal gut bacterium remove acetylations from all positions on complex beta-mannans.; Proc.Natl.Acad.Sci.USA, 117:7122-7130, 2020; PubMed: 32170022; DOI: 10.1073/pnas.1915376117

実験手法

X-RAY DIFFRACTION (2.4 Å)