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6HGY

CRYSTAL STRUCTURE OF CATHEPSIN K WITH N-DESMETHYL THALASSOSPIRAMIDE C

Summary for 6HGY
Entry DOI10.2210/pdb6hgy/pdb
DescriptorCathepsin K, THALASSOSPIRAMIDE C (3 entities in total)
Functional Keywordsprotease, cathepsin k, proteros biostructures gmbh, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight24315.45
Authors
Zakarian, A.,Buckman, B.O.,Adler, M.,Griessner, A.,Blaesse, M. (deposition date: 2018-08-23, release date: 2019-06-26, Last modification date: 2024-01-17)
Primary citationFournier, J.,Chen, K.,Mailyan, A.K.,Jackson, J.J.,Buckman, B.O.,Emayan, K.,Yuan, S.,Rajagopalan, R.,Misialek, S.,Adler, M.,Blaesse, M.,Griessner, A.,Zakarian, A.
Total Synthesis of Covalent Cysteine Protease Inhibitor N-Desmethyl Thalassospiramide C and Crystallographic Evidence for Its Mode of Action.
Org.Lett., 21:508-512, 2019
Cited by
PubMed: 30628449
DOI: 10.1021/acs.orglett.8b03821
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.2 Å)
Structure validation

217705

数据于2024-03-27公开中

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