6HFW

Mycobacterium tuberculosis DprE1 in complex with CMP1

6HFW の概要

• エントリーDOI: 10.2210/pdb6hfw/pdb
• 分子名称: Decaprenylphosphoryl-beta-D-ribose oxidase, FLAVIN-ADENINE DINUCLEOTIDE, IMIDAZOLE, ... (5 entities in total)
• 機能のキーワード: oxidoreductase, oxidoreductase inhibitor
• 由来する生物種: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 106008.19

構造登録者

Chung, C. (登録日: 2018-08-21, 公開日: 2018-09-19, 最終更新日: 2024-05-15)

• 主引用文献: Richter, A.,Rudolph, I.,Mollmann, U.,Voigt, K.,Chung, C.W.,Singh, O.M.P.,Rees, M.,Mendoza-Losana, A.,Bates, R.,Ballell, L.,Batt, S.,Veerapen, N.,Futterer, K.,Besra, G.,Imming, P.,Argyrou, A.; Novel insight into the reaction of nitro, nitroso and hydroxylamino benzothiazinones and of benzoxacinones with Mycobacterium tuberculosis DprE1.; Sci Rep, 8:13473-13473, 2018; PubMed: 30194385; DOI: 10.1038/s41598-018-31316-6

実験手法

X-RAY DIFFRACTION (2.47 Å)