6HFH

Human dihydroorotase mutant F1563A co-crystallized with carbamoyl aspartate at pH 7.0

6HFH の概要

• エントリーDOI: 10.2210/pdb6hfh/pdb
• 分子名称: CAD protein, ZINC ION, FORMIC ACID, ... (5 entities in total)
• 機能のキーワード: de novo pyrimidine biosynthesis, cad, tim-barrel, carboxylated lysine, biosynthetic protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 43397.74

構造登録者

Ramon-Maiques, S.,Grande Garcia, A. (登録日: 2018-08-21, 公開日: 2018-10-24, 最終更新日: 2024-01-17)

• 主引用文献: Del Cano-Ochoa, F.,Grande-Garcia, A.,Reverte-Lopez, M.,D'Abramo, M.,Ramon-Maiques, S.; Characterization of the catalytic flexible loop in the dihydroorotase domain of the human multi-enzymatic protein CAD.; J. Biol. Chem., 293:18903-18913, 2018; PubMed: 30315107; DOI: 10.1074/jbc.RA118.005494

実験手法

X-RAY DIFFRACTION (1.44871265165 Å)