6HAF

Pyruvate oxidase variant E59Q from L. plantarum in complex with phosphate

Summary for 6HAF

Entry DOI	10.2210/pdb6haf/pdb
Related	4kgd
Descriptor	Pyruvate oxidase, FLAVIN-ADENINE DINUCLEOTIDE, POTASSIUM ION, ... (8 entities in total)
Functional Keywords	carbanion, structure activity relationship, oxidation-reduction, umpolung, thiamine diphosphate, reaction intermediate, flavin adenine dinucleotide, oxidoreductase
Biological source	Lactobacillus plantarum
Total number of polymer chains	2
Total formula weight	136255.23
Authors	Funk, L.M.,Sautner, V.,Tittmann, K. (deposition date: 2018-08-07, release date: 2019-08-21, Last modification date: 2021-08-04)
Primary citation	Dai, S.,Funk, L.M.,von Pappenheim, F.R.,Sautner, V.,Paulikat, M.,Schroder, B.,Uranga, J.,Mata, R.A.,Tittmann, K. Low-barrier hydrogen bonds in enzyme cooperativity. Nature, 573:609-613, 2019 Cited by PubMed: 31534226 DOI: 10.1038/s41586-019-1581-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.3 Å)

Structure validation