6H9J
Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPV3 (229-255)
Summary for 6H9J
Entry DOI | 10.2210/pdb6h9j/pdb |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, Transient receptor potential cation channel subfamily V member 3, N-OXALYLGLYCINE, ... (7 entities in total) |
Functional Keywords | non-heme, dioxygenase, oxygenase, metal-binding, transcription, dsbh, facial triad, asparaginyl/aspartyl hydroxylase, signaling, ard, beta-hydroxylation, activator-inhibitor, oxidoreductase-peptide complex, oxidoreductase ankyrin, channel, protein binding, ion channel, trpv channel, membrane protein, gene regulation |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 42385.68 |
Authors | Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J. (deposition date: 2018-08-04, release date: 2019-08-14, Last modification date: 2024-01-17) |
Primary citation | Leissing, T.M.,Clifton, I.J.,Saward, B.G.,Lu, X.,Hopkinson, R.J.,Schofield, C.J. Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPV3 (229-255) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.83 Å) |
Structure validation
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