6H5R

Structure of the complex of a human telomeric DNA with bis(1-butyl-3-methyl-imidazole-2-ylidene) gold(I)

6H5R の概要

• エントリーDOI: 10.2210/pdb6h5r/pdb
• 分子名称: Human Telomeric DNA, POTASSIUM ION, STRONTIUM ION, ... (5 entities in total)
• 機能のキーワード: drug-dna complex, g quadruplex, dna
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 9651.25

構造登録者

Bazzicalupi, C.,Gratteri, P.,Papi, F. (登録日: 2018-07-25, 公開日: 2019-01-30, 最終更新日: 2024-01-17)

• 主引用文献: Guarra, F.,Marzo, T.,Ferraroni, M.,Papi, F.,Bazzicalupi, C.,Gratteri, P.,Pescitelli, G.,Messori, L.,Biver, T.,Gabbiani, C.; Interaction of a gold(i) dicarbene anticancer drug with human telomeric DNA G-quadruplex: solution and computationally aided X-ray diffraction analysis.; Dalton Trans, 47:16132-16138, 2018; PubMed: 30378627; DOI: 10.1039/c8dt03607a

実験手法

X-RAY DIFFRACTION (2 Å)