6GYX

Crystal structure of DacA from Staphylococcus aureus in complex with ApCpp

6GYX の概要

• エントリーDOI: 10.2210/pdb6gyx/pdb
• 分子名称: Diadenylate cyclase, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, MANGANESE (II) ION (3 entities in total)
• 機能のキーワード: c-di-amp, diadenylate cyclase, apcpp, transferase
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 39863.48

構造登録者

Tosi, T.,Freemont, P.S.,Grundling, A. (登録日: 2018-07-02, 公開日: 2019-01-23, 最終更新日: 2024-01-17)

• 主引用文献: Tosi, T.,Hoshiga, F.,Millership, C.,Singh, R.,Eldrid, C.,Patin, D.,Mengin-Lecreulx, D.,Thalassinos, K.,Freemont, P.,Grundling, A.; Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM.; PLoS Pathog., 15:e1007537-e1007537, 2019; PubMed: 30668586; DOI: 10.1371/journal.ppat.1007537

実験手法

X-RAY DIFFRACTION (2.6 Å)