6GYT

Transcription factor dimerization activates the p300 acetyltransferase

Summary for 6GYT

• Entry DOI: 10.2210/pdb6gyt/pdb
• Descriptor: Histone acetyltransferase p300, Histone H4, ZINC ION, ... (5 entities in total)
• Functional Keywords: p300, cbp, acetyltransferase, chromatin, transcriptional regulation, gene regulation
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 39661.25

Authors

Panne, D.,Ortega, E. (deposition date: 2018-07-01, release date: 2018-10-17, Last modification date: 2024-01-17)

• Primary citation: Ortega, E.,Rengachari, S.,Ibrahim, Z.,Hoghoughi, N.,Gaucher, J.,Holehouse, A.S.,Khochbin, S.,Panne, D.; Transcription factor dimerization activates the p300 acetyltransferase.; Nature, 562:538-544, 2018; PubMed: 30323286; DOI: 10.1038/s41586-018-0621-1

Experimental method

X-RAY DIFFRACTION (2.5 Å)