6GYO
Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel in complex with cAMP
Summary for 6GYO
Entry DOI | 10.2210/pdb6gyo/pdb |
EMDB information | 0094 |
Descriptor | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... (6 entities in total) |
Functional Keywords | ion channel, pacemaker current, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 276378.30 |
Authors | Shintre, C.A.,Pike, A.C.W.,Tessitore, A.,Young, M.,Bushell, S.R.,Strain-Damerell, C.,Mukhopadhyay, S.,Burgess-Brown, N.A.,Huiskonen, J.T.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2018-06-30, release date: 2019-05-01, Last modification date: 2024-05-15) |
Primary citation | Shintre, C.A.,Pike, A.C.W.,Tessitore, A.,Young, M.,Bushell, S.R.,Strain-Damerell, C.,Mukhopadhyay, S.,Burgess-Brown, N.A.,Huiskonen, J.T.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Carpenter, E.P. Structure of human HCN4 hyperpolarization-activated cyclic nucleotide-gated ion channel To Be Published, |
Experimental method | ELECTRON MICROSCOPY (3.4 Å) |
Structure validation
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