6GY5

Crystal structure of the kelch domain of human KLHL20 in complex with DAPK1 peptide

6GY5 の概要

• エントリーDOI: 10.2210/pdb6gy5/pdb
• 分子名称: Kelch-like protein 20, Death-associated protein kinase 1, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: complex, e3 ligase, substrate, ubiquitination, kelch domain, death domain, ligase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35274.69

構造登録者

Chen, Z.,Hozjan, V.,Strain-Damerell, C.,Williams, E.,Wang, D.,Cooper, C.D.O.,Sanvitale, C.E.,Fairhead, M.,Carpenter, E.P.,Pike, A.C.W.,Krojer, T.,Srikannathasan, V.,Sorrell, F.,Johansson, C.,Mathea, S.,Burgess-Brown, N.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Bullock, A.N. (登録日: 2018-06-28, 公開日: 2018-08-08, 最終更新日: 2024-01-17)

• 主引用文献: Chen, Z.,Picaud, S.,Filippakopoulos, P.,D'Angiolella, V.,Bullock, A.N.; Structural Basis for Recruitment of DAPK1 to the KLHL20 E3 Ligase.; Structure, 27:1395-1404.e4, 2019; PubMed: 31279627; DOI: 10.1016/j.str.2019.06.005

実験手法

X-RAY DIFFRACTION (1.086 Å)