6GXY
Tryparedoxin from Trypanosoma brucei in complex with CFT
Summary for 6GXY
| Entry DOI | 10.2210/pdb6gxy/pdb |
| Related | 6GXG |
| Descriptor | Tryparedoxin, 5-(4-fluorophenyl)-2-methyl-3~{H}-thieno[2,3-d]pyrimidin-4-one (3 entities in total) |
| Functional Keywords | covalent inhibitor, photoreduction, inhibitor-induced dimerization, monomer-dimer mixture, oxidoreductase |
| Biological source | Trypanosoma brucei brucei |
| Total number of polymer chains | 3 |
| Total formula weight | 48837.99 |
| Authors | Bader, N.,Wagner, A.,Hellmich, U.,Schindelin, H. (deposition date: 2018-06-27, release date: 2019-01-16, Last modification date: 2024-01-17) |
| Primary citation | Wagner, A.,Le, T.A.,Brennich, M.,Klein, P.,Bader, N.,Diehl, E.,Paszek, D.,Weickhmann, A.K.,Dirdjaja, N.,Krauth-Siegel, R.L.,Engels, B.,Opatz, T.,Schindelin, H.,Hellmich, U.A. Inhibitor-Induced Dimerization of an Essential Oxidoreductase from African Trypanosomes. Angew. Chem. Int. Ed. Engl., 58:3640-3644, 2019 Cited by PubMed: 30605929DOI: 10.1002/anie.201810470 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
Download full validation report
