6GX9

Crystal structure of the TNPO3 - CPSF6 RSLD complex

Summary for 6GX9

Entry DOI	10.2210/pdb6gx9/pdb
Descriptor	Transportin-3, Cleavage and polyadenylation specificity factor subunit 6, MAGNESIUM ION, ... (6 entities in total)
Functional Keywords	karyopherin-cargo complex, nuclear import, sr-like domain, nuclear protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	227920.07
Authors	Cherepanov, P.,Cook, N. (deposition date: 2018-06-26, release date: 2019-03-13, Last modification date: 2024-01-17)
Primary citation	Jang, S.,Cook, N.J.,Pye, V.E.,Bedwell, G.J.,Dudek, A.M.,Singh, P.K.,Cherepanov, P.,Engelman, A.N. Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6. Nucleic Acids Res., 47:4663-4683, 2019 Cited by PubMed: 30916345 DOI: 10.1093/nar/gkz206 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation