6GX9

Crystal structure of the TNPO3 - CPSF6 RSLD complex

6GX9 の概要

• エントリーDOI: 10.2210/pdb6gx9/pdb
• 分子名称: Transportin-3, Cleavage and polyadenylation specificity factor subunit 6, MAGNESIUM ION, ... (6 entities in total)
• 機能のキーワード: karyopherin-cargo complex, nuclear import, sr-like domain, nuclear protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 227920.07

構造登録者

Cherepanov, P.,Cook, N. (登録日: 2018-06-26, 公開日: 2019-03-13, 最終更新日: 2024-01-17)

• 主引用文献: Jang, S.,Cook, N.J.,Pye, V.E.,Bedwell, G.J.,Dudek, A.M.,Singh, P.K.,Cherepanov, P.,Engelman, A.N.; Differential role for phosphorylation in alternative polyadenylation function versus nuclear import of SR-like protein CPSF6.; Nucleic Acids Res., 47:4663-4683, 2019; PubMed: 30916345; DOI: 10.1093/nar/gkz206

実験手法

X-RAY DIFFRACTION (2.7 Å)