6GWJ

Human OSGEP / LAGE3 / GON7 complex

Summary for 6GWJ

Entry DOI	10.2210/pdb6gwj/pdb
Descriptor	EKC/KEOPS complex subunit LAGE3, EKC/KEOPS complex subunit GON7, Probable tRNA N6-adenosine threonylcarbamoyltransferase, ... (8 entities in total)
Functional Keywords	trna, t6a modification, rna binding protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	63915.47
Authors	Missoury, S.,Liger, D.,Durand, D.,Collinet, B.,Tilbeurgh, V.H. (deposition date: 2018-06-25, release date: 2019-07-03, Last modification date: 2024-05-15)
Primary citation	Arrondel, C.,Missoury, S.,Snoek, R.,Patat, J.,Menara, G.,Collinet, B.,Liger, D.,Durand, D.,Gribouval, O.,Boyer, O.,Buscara, L.,Martin, G.,Machuca, E.,Nevo, F.,Lescop, E.,Braun, D.A.,Boschat, A.C.,Sanquer, S.,Guerrera, I.C.,Revy, P.,Parisot, M.,Masson, C.,Boddaert, N.,Charbit, M.,Decramer, S.,Novo, R.,Macher, M.A.,Ranchin, B.,Bacchetta, J.,Laurent, A.,Collardeau-Frachon, S.,van Eerde, A.M.,Hildebrandt, F.,Magen, D.,Antignac, C.,van Tilbeurgh, H.,Mollet, G. Defects in t 6 A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome. Nat Commun, 10:3967-3967, 2019 Cited by PubMed: 31481669 DOI: 10.1038/s41467-019-11951-x PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation