6GWJ

Human OSGEP / LAGE3 / GON7 complex

6GWJ の概要

• エントリーDOI: 10.2210/pdb6gwj/pdb
• 分子名称: EKC/KEOPS complex subunit LAGE3, EKC/KEOPS complex subunit GON7, Probable tRNA N6-adenosine threonylcarbamoyltransferase, ... (8 entities in total)
• 機能のキーワード: trna, t6a modification, rna binding protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 63915.47

構造登録者

Missoury, S.,Liger, D.,Durand, D.,Collinet, B.,Tilbeurgh, V.H. (登録日: 2018-06-25, 公開日: 2019-07-03, 最終更新日: 2024-05-15)

• 主引用文献: Arrondel, C.,Missoury, S.,Snoek, R.,Patat, J.,Menara, G.,Collinet, B.,Liger, D.,Durand, D.,Gribouval, O.,Boyer, O.,Buscara, L.,Martin, G.,Machuca, E.,Nevo, F.,Lescop, E.,Braun, D.A.,Boschat, A.C.,Sanquer, S.,Guerrera, I.C.,Revy, P.,Parisot, M.,Masson, C.,Boddaert, N.,Charbit, M.,Decramer, S.,Novo, R.,Macher, M.A.,Ranchin, B.,Bacchetta, J.,Laurent, A.,Collardeau-Frachon, S.,van Eerde, A.M.,Hildebrandt, F.,Magen, D.,Antignac, C.,van Tilbeurgh, H.,Mollet, G.; Defects in t 6 A tRNA modification due to GON7 and YRDC mutations lead to Galloway-Mowat syndrome.; Nat Commun, 10:3967-3967, 2019; PubMed: 31481669; DOI: 10.1038/s41467-019-11951-x

実験手法

X-RAY DIFFRACTION (1.95 Å)