6GVJ
Human Mps1 kinase domain with ordered activation loop
Summary for 6GVJ
Entry DOI | 10.2210/pdb6gvj/pdb |
Descriptor | Dual specificity protein kinase TTK, GLYCEROL, CHLORIDE ION, ... (4 entities in total) |
Functional Keywords | mps1, ttk, kinase, mitosis checkpoint, transferase, activation loop, activation segment |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 49496.04 |
Authors | Roorda, J.C.,Hiruma, Y.,Joosten, R.P.,Perrakis, A. (deposition date: 2018-06-21, release date: 2019-01-09, Last modification date: 2024-01-17) |
Primary citation | Roorda, J.C.,Joosten, R.P.,Perrakis, A.,Hiruma, Y. A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop. Proteins, 87:348-352, 2019 Cited by PubMed: 30582207DOI: 10.1002/prot.25651 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.41 Å) |
Structure validation
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