6GRZ

Crystal structure of the light chain dimer mH6

Summary for 6GRZ

• Entry DOI: 10.2210/pdb6grz/pdb
• Related: 5MUD
• Descriptor: mH6, GLYCEROL (3 entities in total)
• Functional Keywords: light chain dimer, light chain amyloidosis, immunoglobulin fold, protein aggregation, immune system
• Biological source: Homo sapiens
• Total number of polymer chains: 2
• Total formula weight: 46129.07

Authors

Maritan, M.,Ricagno, S.,Ambrosetti, A.,Oberti, L. (deposition date: 2018-06-13, release date: 2019-06-12, Last modification date: 2024-01-17)

• Primary citation: Maritan, M.,Romeo, M.,Oberti, L.,Sormanni, P.,Tasaki, M.,Russo, R.,Ambrosetti, A.,Motta, P.,Rognoni, P.,Mazzini, G.,Barbiroli, A.,Palladini, G.,Vendruscolo, M.,Diomede, L.,Bolognesi, M.,Merlini, G.,Lavatelli, F.,Ricagno, S.; Inherent Biophysical Properties Modulate the Toxicity of Soluble Amyloidogenic Light Chains; J.Mol.Biol., 2020; DOI: 10.1016/j.jmb.2019.12.015

Experimental method

X-RAY DIFFRACTION (2.1 Å)