6GRP

Crystal Structure Of Human Transthyretin in complex with 3,5,6-trichloro-2-pyridinol (TC2P)

6GRP の概要

• エントリーDOI: 10.2210/pdb6grp/pdb
• 分子名称: Transthyretin, 3,5,6-trichloro-2-pyridinol, SODIUM ION, ... (4 entities in total)
• 機能のキーワード: transthyretin, transport protein, thyroxine disrupting chemicals, tdcs, 3, 5, 6-trichloro-2-pyridinol, tc2p
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28371.45

構造登録者

Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (登録日: 2018-06-12, 公開日: 2018-07-11, 最終更新日: 2024-01-17)

• 主引用文献: Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E.; Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.; Environ. Sci. Technol., 52:11865-11874, 2018; PubMed: 30226982; DOI: 10.1021/acs.est.8b03581

実験手法

X-RAY DIFFRACTION (1.6 Å)