6GR7
Crystal Structure Of Human Transthyretin in complex with 2,4,5-trichlorophenoxyacetic acid (2,4,5-T)
Summary for 6GR7
Entry DOI | 10.2210/pdb6gr7/pdb |
Descriptor | Transthyretin, 2-[2,4,5-tris(chloranyl)phenoxy]ethanoic acid (3 entities in total) |
Functional Keywords | transthyretin, transport protein, thyroxine disrupting chemicals, tdcs, 2, 4, 5-trichlorophenoxyacetic acid, 5-t |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 28065.68 |
Authors | Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (deposition date: 2018-06-09, release date: 2018-07-11, Last modification date: 2024-01-17) |
Primary citation | Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environ. Sci. Technol., 52:11865-11874, 2018 Cited by PubMed: 30226982DOI: 10.1021/acs.est.8b03581 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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