6GR7

Crystal Structure Of Human Transthyretin in complex with 2,4,5-trichlorophenoxyacetic acid (2,4,5-T)

6GR7 の概要

• エントリーDOI: 10.2210/pdb6gr7/pdb
• 分子名称: Transthyretin, 2-[2,4,5-tris(chloranyl)phenoxy]ethanoic acid (3 entities in total)
• 機能のキーワード: transthyretin, transport protein, thyroxine disrupting chemicals, tdcs, 2, 4, 5-trichlorophenoxyacetic acid, 5-t
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28065.68

構造登録者

Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (登録日: 2018-06-09, 公開日: 2018-07-11, 最終更新日: 2024-01-17)

• 主引用文献: Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E.; Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.; Environ. Sci. Technol., 52:11865-11874, 2018; PubMed: 30226982; DOI: 10.1021/acs.est.8b03581

実験手法

X-RAY DIFFRACTION (1.4 Å)