6GR0
Petrobactin-binding engineered lipocalin in complex with gallium-petrobactin
Summary for 6GR0
Entry DOI | 10.2210/pdb6gr0/pdb |
Descriptor | Neutrophil gelatinase-associated lipocalin, 4-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-[2-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-oxidanylidene-ethyl]-2-oxidanyl-4-oxidanylidene-butanoic acid, GALLIUM (III) ION, ... (4 entities in total) |
Functional Keywords | anticalin, beta-barrel, petrobactin, lcn2, lipocalin, ngal, protein engineering, transport protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 65202.57 |
Authors | Skerra, A.,Eichinger, A. (deposition date: 2018-06-08, release date: 2018-08-15, Last modification date: 2024-01-17) |
Primary citation | Dauner, M.,Eichinger, A.,Lucking, G.,Scherer, S.,Skerra, A. Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus. Angew. Chem. Int. Ed. Engl., 57:14619-14623, 2018 Cited by PubMed: 30063283DOI: 10.1002/anie.201807442 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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