6GR0

Petrobactin-binding engineered lipocalin in complex with gallium-petrobactin

6GR0 の概要

• エントリーDOI: 10.2210/pdb6gr0/pdb
• 分子名称: Neutrophil gelatinase-associated lipocalin, 4-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-[2-[4-[3-[[3,4-bis(oxidanyl)phenyl]carbonylamino]propylamino]butylamino]-2-oxidanylidene-ethyl]-2-oxidanyl-4-oxidanylidene-butanoic acid, GALLIUM (III) ION, ... (4 entities in total)
• 機能のキーワード: anticalin, beta-barrel, petrobactin, lcn2, lipocalin, ngal, protein engineering, transport protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 65202.57

構造登録者

Skerra, A.,Eichinger, A. (登録日: 2018-06-08, 公開日: 2018-08-15, 最終更新日: 2024-01-17)

• 主引用文献: Dauner, M.,Eichinger, A.,Lucking, G.,Scherer, S.,Skerra, A.; Reprogramming Human Siderocalin To Neutralize Petrobactin, the Essential Iron Scavenger of Anthrax Bacillus.; Angew. Chem. Int. Ed. Engl., 57:14619-14623, 2018; PubMed: 30063283; DOI: 10.1002/anie.201807442

実験手法

X-RAY DIFFRACTION (2.5 Å)