X-ray structure of KH1-2 domain of IMP3

Summary for 6GQE

DescriptorInsulin-like growth factor 2 mRNA-binding protein 3 (2 entities in total)
Functional Keywordsmultidomain-rna binding protein, insulin-like growth factor 2, mrna binding protein 3 (imp3), mrna-protein interactions, rna binding protein
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total molecular weight18626.42
Janowski, R.,Schlundt, A.,Sattler, M.,Niessing, D. (deposition date: 2018-06-07, release date: 2019-04-24, Last modification date: 2019-05-22)
Primary citation
Schneider, T.,Hung, L.-H.,Aziz, M.,Wilmen, A.,Thaum, S.,Wagner, J.,Janowski, R.,Muller, S.,Schreiner, S.,Friedhoff, P.,Huttelmaier, S.,Niessing, D.,Sattler, M.,Schlundt, A.,Bindereif, A.
Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3
Nat Commun, 2019
DOI: 10.1038/s41467-019-09769-8
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.29320 1.4% 8.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 6gqe
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Molmil generated image of 6gqe
rotated about x axis by 90°
Molmil generated image of 6gqe
rotated about y axis by 90°