6GOS

E. coli Microcin synthetase McbBCD complex with pro-MccB17 bound

6GOS の概要

• エントリーDOI: 10.2210/pdb6gos/pdb
• 分子名称: Bacteriocin microcin B17, GLYCEROL, Microcin B17-processing protein McbB, ... (11 entities in total)
• 機能のキーワード: microcin, dna gyrase, heterocyclization, posttranslational modification, biosynthetic protein, antibiotic-inhibitor complex, antibiotic/inhibitor
• 由来する生物種: Escherichia coli str. K-12 substr. MG1655; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 151889.79

構造登録者

Ghilarov, D.,Stevenson, C.E.M.,Travin, D.Y.,Piskunova, J.,Serebryakova, M.,Maxwell, A.,Lawson, D.M.,Severinov, K. (登録日: 2018-06-04, 公開日: 2019-01-30, 最終更新日: 2019-03-06)

• 主引用文献: Ghilarov, D.,Stevenson, C.E.M.,Travin, D.Y.,Piskunova, J.,Serebryakova, M.,Maxwell, A.,Lawson, D.M.,Severinov, K.; Architecture of Microcin B17 Synthetase: An Octameric Protein Complex Converting a Ribosomally Synthesized Peptide into a DNA Gyrase Poison.; Mol. Cell, 73:749-762.e5, 2019; PubMed: 30661981; DOI: 10.1016/j.molcel.2018.11.032

実験手法

X-RAY DIFFRACTION (2.1 Å)