6GO4

TdT chimera (Loop1 of pol mu) - binary complex with ddCTP

6GO4 の概要

• エントリーDOI: 10.2210/pdb6go4/pdb
• 分子名称: DNA nucleotidylexotransferase,DNA-directed DNA/RNA polymerase mu,DNA nucleotidylexotransferase, SODIUM ION, MAGNESIUM ION, ... (5 entities in total)
• 機能のキーワード: nhej pathway, dna bridging, dna polymerase polx, dna binding protein
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 46347.44

構造登録者

Loc'h, J.,Gerodimos, C.A.,Rosario, S.,Lieber, M.R.,Delarue, M. (登録日: 2018-06-01, 公開日: 2019-06-05, 最終更新日: 2024-01-17)

• 主引用文献: Loc'h, J.,Gerodimos, C.A.,Rosario, S.,Tekpinar, M.,Lieber, M.R.,Delarue, M.; Structural evidence for an intransbase selection mechanism involving Loop1 in polymerase mu at an NHEJ double-strand break junction.; J.Biol.Chem., 294:10579-10595, 2019; PubMed: 31138645; DOI: 10.1074/jbc.RA119.008739

実験手法

X-RAY DIFFRACTION (1.96 Å)