6GNR

Crystal Structure Of Sea Bream Transthyretin in complex with 2-(3-chloro-2-methylanilino)pyridine-3-carboxylic acid (Clonixin)

6GNR の概要

• エントリーDOI: 10.2210/pdb6gnr/pdb
• 分子名称: Transthyretin, 2-(3-chloro-2-methylanilino)pyridine-3-carboxylic acid (3 entities in total)
• 機能のキーワード: transthyretin, transport protein, thyroxine disrupting chemicals, tdcs, 2-(3-chloro-2-methylanilino)pyridine-3-carboxylic acid, clonixin
• 由来する生物種: Sparus aurata (Gilthead seabream)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 29435.58

構造登録者

Grundstrom, C.,Zhang, J.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E. (登録日: 2018-05-31, 公開日: 2018-07-11, 最終更新日: 2024-01-17)

• 主引用文献: Zhang, J.,Grundstrom, C.,Brannstrom, K.,Iakovleva, I.,Lindberg, M.,Olofsson, A.,Andersson, P.L.,Sauer-Eriksson, A.E.; Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals.; Environ. Sci. Technol., 52:11865-11874, 2018; PubMed: 30226982; DOI: 10.1021/acs.est.8b03581

実験手法

X-RAY DIFFRACTION (1.4 Å)