6GNN
Exoenzyme T from Pseudomonas aeruginosa in complex with human 14-3-3 protein beta, tetrameric crystal form bound to STO1101
Summary for 6GNN
Entry DOI | 10.2210/pdb6gnn/pdb |
Descriptor | 14-3-3 protein beta/alpha, Exoenzyme T, 3-(12-oxidanylidene-7-thia-9,11-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),2(6),9-trien-10-yl)propanoic acid (3 entities in total) |
Functional Keywords | exot, pseudomonas aeruginosa, adp-ribosylation, nad, toxin |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 55554.55 |
Authors | Karlberg, T.,Pinto, A.F.,Hornyak, P.,Thorsell, A.G.,Nareoja, K.,Schuler, H. (deposition date: 2018-05-31, release date: 2018-09-26, Last modification date: 2024-01-17) |
Primary citation | Karlberg, T.,Hornyak, P.,Pinto, A.F.,Milanova, S.,Ebrahimi, M.,Lindberg, M.,Pullen, N.,Nordstrom, A.,Loverli, E.,Caraballo, R.,Wong, E.V.,Nareoja, K.,Thorsell, A.G.,Elofsson, M.,De La Cruz, E.M.,Bjorkegren, C.,Schuler, H. 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nat Commun, 9:3785-3785, 2018 Cited by PubMed: 30224724DOI: 10.1038/s41467-018-06194-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.79 Å) |
Structure validation
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